Available Properties

Palmyra, Missouri is the
perfect place for your business!

Our community is located between two large towns, Hannibal, MO and Quincy, IL and has over 3,500 residents who shop and use services in Palmyra.

Current Available
Commercial Properties:


City of Palmyra
This 22.4 acre property is located off Highway 168 just outside of Palmyra. Adjacent properties are under development, and this great location could be too.


Tom Whiston Property

Located next to the old Crowns Shoe Rack building, this 6.2 acres overlooks highway 61. Nearby commercial, residential, and industrial development are taking place. This gem is waiting for the right buyer

423 Short Street

This metal building used to house Jet Bulk Oil. It is near the water tower in an industrial part of town. This building is a great size for an expanding business and has a big lot for parking. This building and large lot has endless possibilities.


502 E Ross Street & 504 E Ross Street

502 E Ross Street: This large building used to be home to Shopko. It would be a great building for another large store or an expanding business. The parking lot is ample, and the access from Highway 61 makes it a desirable location. 504 E Ross Street: This building is in a prime location. With easy access off of Highway 61, this building could be used as a storefront, a warehouse, or for an expanding business. This building used to the site of C&R Market, and has a large parking lot attached to it. Both buildings have 15,000 square feet and three phase power.


Greisbaums Residential Development

The South end of Palmyra has seen rapid development in the last couple of years. Greisbaums residential development is a great example of how the town is growing, and a great opportunity for new families entering the region.


Palmyra Industrial Park

Palmyra’s highway 61 adjacent industrial park is ideal for new business and industry. Conveniently located near all the amenities a growing business could ask for.


103 South Main (lot only for sale)

This lot sits on a corner of Palmyra’s busiest street, Main Street. The building has been demolished, but the lot provides the possibilities for what it could be are endless. Sitting next to Chevy’s Lounge and down the street from Rebel Pig, it’s in a prime location in Palmyra.


107 South Main

This building boasts an impressive stone and brick front. Upstairs is a 3 BR, 1 bath apartment. The lower level is an unfinished office space, which could be altered to the owner’s needs. It is in a great location in Palmyra, directly across from the courthouse.


111 South Main

This 2-story building is actually 2 storefronts in one. Currently being used for storage, it’s a large building that could house a large company. Located on Main Street, it’s in a prime location.


113 South Main

This 2-story building has been used as an appliance store. Currently sitting empty, it would need some TLC to be used again as a storefront or office space. It would be a great space for a new owner. It is in a prime location, located in the 100 block of South Main Street.


115-117 South Main

This 2-story building with 2 storefronts sits next to the Rebel Pig Restaurant on Main Street in Palmyra. Directly across from the courthouse, it’s in a prime location. There are so many possibilities for the use of this building!


206 South Main

The 2-story former Gambles building sits right off of Main Street. While it needs some TLC to restore it to its former grandeur, it is structurally sound. It just needs the right owner with a vision. It sits right off Main Street, and is surrounded by businesses.


308A South Main

The storefront in this 2-story building at 308 Main Street is just waiting to be claimed. There is an already established business next door. Located in a prime location, it could be used to house a business or store.


314 South Main

This 2-story building needs some TLC, but it could boast an impressive storefront for the right business. Located next to the Cleaners in Palmyra, it is in a prime location right off of Main Street.


Thompson Street

This is the site of the former Bud’s Paint and Body Shop location. This is a prime location for the right business. It’s virtually move in ready, and it would make a great location for a garage or body shop, or an automotive dealership.


411 Marion City Road (occupied)

This building, located off of Marion City Road, has been used as a store in the past. It’s virtually move in ready and in great shape. It just needs a business to call it home. It can be used as a store again, or as a large office space for a new company.


Marion City Road (occupied)

This building and lot used to be an automotive dealership, and it is beckoning for a new owner. Located off of Highway 61, this building is in a great location and easily accessible. The lot looks brand new!